Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | SHBG | P04278 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GANAB | Q14697 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324600 | 0.90 | TSHR (0.38) | GBA1SHBGKDM4ETSHRHSD17B10 | |
| SCHEMBL11210679 | 0.87 | CA1 (0.38) | GBA1CA1CA2CA4TRPA1 | |
| SCHEMBL4845164 | 0.86 | CA1 (0.37) | GBA1SHBGKDM4ETSHRHSD17B10 | |
| SCHEMBL13104323 | 0.86 | CA1 (0.37) | GBA1SHBGKDM4ETSHRHSD17B10 | |
| SCHEMBL12886104 | 0.86 | CA1 (0.37) | GBA1SHBGKDM4ETSHRHSD17B10 | |
| SCHEMBL12166853 | 0.86 | CA1 (0.35) | GBA1CA1CA2CA4 | |
| SCHEMBL6909002 | 0.84 | CA1 (0.34) | GBA1CA1CA2CA4 | |
| SCHEMBL18595189 | 0.81 | CA1 (0.41) | GBA1SHBGKDM4ETSHRHSD17B10 | |
| SCHEMBL25692572 | 0.81 | CA1 (0.41) | GBA1SHBGKDM4ETSHRHSD17B10 | |
| SCHEMBL4840529 | 0.81 | CA1 (0.41) | GBA1SHBGKDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9012497-B2 | Cyclohexyl carbamate compounds as active anti-cellulite ingredients | SYMRISE AG (DE) | 2015-04-21 | — | — | US | disclosed |
| US-9012497-B2 | Cyclohexyl carbamate compounds as active anti-cellulite ingredients | SYMRISE AG (DE) | 2015-04-21 | — | — | US | disclosed |
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130137710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE AG (DE) | 2013-05-30 | — | — | US | disclosed |
| US-20130137710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE AG (DE) | 2013-05-30 | — | — | US | disclosed |
| EP-2389922-A1 | Cyclohexyl carbamate compounds as anti-ageing actives | Symrise AG (DE) | 2011-11-30 | — | — | EP | disclosed |
| EP-1971568-B1 | PROCESS FOR CONTINUOUS PREPARATION OF A PRIMARY AROMATIC AMINE | BASF SE (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20090076306-A1 | PROCESS FOR CONTINUOUS PREPARATION OF A PRIMARY AROMATIC AMINE | BASF SE (DE) | 2009-03-19 | — | — | US | disclosed |
| EP-1971568-A1 | PROCESS FOR CONTINUOUS PREPARATION OF A PRIMARY AROMATIC AMINE | BASF SE (DE) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007077148-A1 | PROCESS FOR CONTINUOUS PREPARATION OF A PRIMARY AROMATIC AMINE | BASF SE (DE) | 2007-07-12 | — | — | WO | disclosed |
| EP-0050229-B1 | PROCESS FOR THE PREPARATION OF PRIMARY AROMATIC AMINES FROM CYCLIC ALCOHOLS AND/OR KETONES | BASF Aktiengesellschaft (DE) | 1983-09-28 | — | — | EP | disclosed |
| US-4355180-A | Preparation of primary aromatic amines from cyclic alcohols and/or ketones | BASF AKTIENGESELLSCHAFT (DE) | 1982-10-19 | — | — | US | disclosed |
| EP-0050229-A1 | Process for the preparation of primary aromatic amines from cyclic alcohols and/or ketones | BASF Aktiengesellschaft (DE) | 1982-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | CBR1, CYP2A13, CBR3 | GBA1 2742/4885SHBG 186/4885KDM4E 724/4885 |
| US-20130137710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | CBR1, NCOR2, CECR2 | GBA1 3124/4885SHBG 231/4885KDM4E 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.