Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | GANAB | Q14697 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307844 | 0.90 | GBA1 (0.34) | TSHRKDM4EHSD17B10SHBGTRPA1 | |
| SCHEMBL12166885 | 0.83 | KDM4E (0.33) | TSHRKDM4EHSD17B10TRPA1TRPM8 | |
| SCHEMBL6326545 | 0.80 | SHBG (0.33) | TSHRKDM4EHSD17B10SHBG | |
| SCHEMBL6326491 | 0.78 | CYP1A2 (0.31) | TSHRKDM4EHSD17B10GBA1 | |
| SCHEMBL12166664 | 0.78 | KDM4E (0.33) | TSHRKDM4EHSD17B10TRPA1TRPM8 | |
| SCHEMBL11210679 | 0.78 | CA1 (0.38) | TRPA1TRPM8GBA1 | |
| SCHEMBL6322640 | 0.77 | ALOX5 (0.34) | GBA1 | |
| SCHEMBL12166853 | 0.77 | CA1 (0.35) | GBA1 | |
| SCHEMBL14373095 | 0.76 | — | — | |
| SCHEMBL4840529 | 0.75 | CA1 (0.41) | TSHRKDM4EHSD17B10SHBGTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009928-A1 | Cyclopentanone derivative | ZEON CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1420005-A1 | CYCLOPENTANONE DERIVATIVE | Zeon Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009928-A1 | Cyclopentanone derivative | PTGIS, CYP51A1, TRPA1 | TSHR 4837/4885KDM4E 2486/4885HSD17B10 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.