Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23080475 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP1A2CYP2C9ALDH1A1MEN1 | |
| SCHEMBL13918272 | 0.73 | MEN1 (0.48) | SMN1; SMN2CYP1A2CYP2C9ALDH1A1MEN1 | |
| SCHEMBL9024849 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP1A2CYP2C9ALDH1A1KMT2A | |
| SCHEMBL3131565 | 0.68 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP1A2CYP2C9ALDH1A1MEN1 | |
| SCHEMBL5725151 | 0.68 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL6167293 | 0.67 | HTT (0.42) | ALDH1A1LMNAKDM4EHTTTSHR | |
| SCHEMBL21612274 | 0.65 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL6166704 | 0.62 | HTT (0.64) | LMNAHTTTSHR | |
| SCHEMBL1582995 | 0.61 | HTR7 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9024154 | 0.61 | HTR7 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043190-A1 | ISOXAZOLO[5,4-H]QUINAZOLINE COMPOUNDS AS PROTEIN KINASE INHIBITORS | 成都赛诺希亚生物科技有限公司 | 2021-03-11 | — | — | WO | disclosed |