Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21563866 | 0.84 | MAPT (0.53) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL1668058 | 0.81 | NPC1 (0.71) | KDM4EALDH1A1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10568444 | 0.71 | SRC (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL853240 | 0.70 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL22976049 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL5924831 | 0.70 | NPC1 (0.80) | KDM4EALDH1A1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL730536 | 0.69 | MAPT (0.73) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL16989247 | 0.67 | HPGD (0.49) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL27584609 | 0.67 | KLKB1 (0.61) | KDM4EALDH1A1 | |
| SCHEMBL14307992 | 0.67 | PARP1 (0.54) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002796-A1 | QUALITY CONTROL OF LNA OLIGONUCLEOTIDE THERAPEUTICS USING MASSIVELY PARALLEL SEQUENCING | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2022-01-06 | — | — | US | disclosed |
| US-20210071247-A1 | MASSIVELY PARALLEL DISCOVERY METHODS FOR OLIGONUCLEOTIDE THERAPEUTICS | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2021-03-11 | — | — | US | disclosed |