SCHEMBL2308337

SCHEMBL2308337

CC(=O)OCCCCc1ccc(I)cc1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.45
HRH3 Q9Y5N1 1/20 0.45
TNKS2 Q9H2K2 1/20 0.43
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.41
FFAR1 O14842 1/20 0.40
NAAA Q02083 1/20 0.39
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1263885 0.98 HRH4 (0.44) HRH4HRH3TNKS2ALDH1A1LMNA
SCHEMBL2310305 0.98 HRH4 (0.44) HRH4HRH3TNKS2ALDH1A1LMNA
SCHEMBL1263483 0.98 HRH4 (0.44) HRH4HRH3TNKS2ALDH1A1LMNA
SCHEMBL2311721 0.95 HRH4 (0.49) HRH4HRH3TNKS2ALDH1A1LMNA
SCHEMBL13777822 0.87 ALDH1A1 (0.41) HRH4HRH3ALDH1A1
SCHEMBL11569838 0.84 HRH4 (0.46) HRH4HRH3LMNAFFAR1
SCHEMBL15809524 0.84 ESR1 (0.52) TNKS2ALDH1A1LMNA
SCHEMBL16673001 0.84 CTDSP1 (0.50) TNKS2ALDH1A1LMNAFFAR1NAAA
SCHEMBL23266623 0.83 FFAR1 (0.44) TNKS2ALDH1A1LMNAFFAR1NAAA
SCHEMBL20706599 0.83 HRH4 (0.49) HRH4HRH3ALDH1A1LMNAFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000855-B1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH CO LTD (JP) 2011-08-03 EP disclosed
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed
EP-2000855-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge Ricoh Company, Ltd. (JP) 2008-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 HRH4 3029/4885HRH3 2149/4885TNKS2 1650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.