Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.38 |
| ▸ | NOS3 | P29474 | 5/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26471836 | 0.76 | USP7 (0.35) | NOS2NOS3NOS1F12PLAU | |
| SCHEMBL21855924 | 0.70 | — | — | |
| SCHEMBL31067767 | 0.70 | — | — | |
| SCHEMBL418596 | 0.69 | — | — | |
| SCHEMBL18328479 | 0.66 | — | — | |
| SCHEMBL17165802 | 0.66 | — | — | |
| SCHEMBL23508892 | 0.66 | — | — | |
| SCHEMBL31144805 | 0.66 | — | — | |
| SCHEMBL31050050 | 0.65 | NOS2 (0.39) | NOS2NOS3NOS1F12PLAU | |
| SCHEMBL31067778 | 0.65 | NOS2 (0.39) | NOS2NOS3NOS1F12PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043077-A1 | SUBSTITUTED PYRAZINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-03-11 | — | — | WO | disclosed |