Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 7/20 | 0.39 |
| ▸ | NOS3 | P29474 | 6/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855909 | 1.00 | NOS2 (0.39) | NOS2NOS3NOS1MAOADYRK1A | |
| SCHEMBL31602251 | 0.78 | NOS2 (0.42) | NOS2NOS3NOS1MAOADYRK1A | |
| SCHEMBL22235384 | 0.77 | NOS3 (0.41) | NOS2NOS3NOS1DYRK1AFYN | |
| SCHEMBL3556163 | 0.77 | NOS2 (0.56) | NOS2NOS3NOS1MAOADYRK1A | |
| SCHEMBL15467137 | 0.75 | NOS3 (0.39) | NOS2NOS3NOS1MAOADYRK1A | |
| SCHEMBL22235846 | 0.75 | DYRK1A (0.41) | NOS2NOS3NOS1MAOADYRK1A | |
| SCHEMBL31395266 | 0.75 | DYRK1A (0.41) | NOS2NOS3NOS1MAOADYRK1A | |
| SCHEMBL3711280 | 0.75 | ALOX5AP (0.41) | NOS2NOS3NOS1MAOADYRK1A | |
| SCHEMBL30323804 | 0.75 | NOS3 (0.39) | NOS2NOS3NOS1MAOADYRK1A | |
| SCHEMBL28163267 | 0.75 | NOS2 (0.39) | NOS2NOS3NOS1MAOADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341124-B | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2024-09-20 | — | — | CN | disclosed |