Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | AGER | Q15109 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12549201 | 0.82 | CYP2C19 (0.47) | HSD17B10CYP2C19KDM4EALDH1A1GAA | |
| SCHEMBL11010296 | 0.73 | KDM4E (0.53) | HSD17B10CYP2C19KDM4EALDH1A1GAA | |
| SCHEMBL20929045 | 0.71 | — | — | |
| SCHEMBL245 | 0.71 | KDM4E (0.59) | HSD17B10CYP2C19KDM4EALDH1A1GAA | |
| SCHEMBL30442868 | 0.70 | KDM4E (0.58) | HSD17B10CYP2C19KDM4EALDH1A1GAA | |
| SCHEMBL28435264 | 0.70 | KDM4E (0.58) | HSD17B10CYP2C19KDM4EALDH1A1GAA | |
| SCHEMBL28606591 | 0.70 | KDM4E (0.58) | HSD17B10CYP2C19KDM4EALDH1A1GAA | |
| SCHEMBL266474 | 0.70 | — | — | |
| SCHEMBL28276330 | 0.70 | KDM4E (0.58) | HSD17B10CYP2C19KDM4EALDH1A1GAA | |
| SCHEMBL28274899 | 0.70 | KDM4E (0.58) | HSD17B10CYP2C19KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046549-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2021-03-11 | — | — | WO | disclosed |