SCHEMBL2308541

SCHEMBL2308541

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(CCCO)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
RARB P10826 6/20 0.40
CYP4A11 Q02928 1/20 0.40
CA2 P00918 2/20 0.39
FDFT1 P37268 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ALDH1A1 P00352 1/20 0.38
RARA P10276 1/20 0.38
MAPT P10636 1/20 0.38
MTOR P42345 1/20 0.38
BACE1 P56817 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2310186 0.95 IGF1R (0.45) IGF1RALOX15MEN1KMT2ARARB
SCHEMBL26295423 0.95 IGF1R (0.46) IGF1RALOX15MEN1KMT2ACYP4A11
SCHEMBL9495382 0.95 IGF1R (0.46) IGF1RALOX15MEN1KMT2ACYP4A11
SCHEMBL14732707 0.94 MEN1 (0.47) MEN1KMT2ARARB
SCHEMBL2307322 0.93 IGF1R (0.44) IGF1RALOX15MEN1KMT2ARARB
SCHEMBL13383868 0.91 MEN1 (0.46) MEN1KMT2ARARBCYP4A11CA2
SCHEMBL12679109 0.89 CYP4F2 (0.42) IGF1RALOX15MEN1KMT2ACYP4A11
SCHEMBL2307510 0.89 CYP4F2 (0.42) IGF1RALOX15MEN1KMT2ACYP4A11
SCHEMBL12679111 0.89 CYP4F2 (0.42) IGF1RALOX15MEN1KMT2ACYP4A11
SCHEMBL15026003 0.89 IGF1R (0.47) IGF1RALOX15MEN1KMT2ARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000855-B1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH CO LTD (JP) 2011-08-03 EP disclosed
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed
EP-2000855-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge Ricoh Company, Ltd. (JP) 2008-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 IGF1R 349/4885ALOX15 2176/4885MEN1 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.