Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 7/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307322 | 0.98 | IGF1R (0.44) | IGF1RALOX15RARBCYP4F2CYP4A11 | |
| SCHEMBL2308541 | 0.95 | IGF1R (0.42) | IGF1RALOX15RARBCYP4A11MEN1 | |
| SCHEMBL18214664 | 0.93 | IGF1R (0.47) | IGF1RALOX15CYP4F2CYP4A11MEN1 | |
| SCHEMBL15025741 | 0.91 | IGF1R (0.47) | IGF1RALOX15RARBMEN1KMT2A | |
| SCHEMBL15026003 | 0.91 | IGF1R (0.47) | IGF1RALOX15RARBMEN1KMT2A | |
| SCHEMBL9495382 | 0.90 | IGF1R (0.46) | IGF1RALOX15CYP4F2CYP4A11MEN1 | |
| SCHEMBL26295423 | 0.90 | IGF1R (0.46) | IGF1RALOX15CYP4F2CYP4A11MEN1 | |
| SCHEMBL14732707 | 0.89 | MEN1 (0.47) | RARBMEN1KMT2A | |
| SCHEMBL12679111 | 0.88 | CYP4F2 (0.42) | IGF1RALOX15CYP4F2CYP4A11MEN1 | |
| SCHEMBL12679109 | 0.88 | CYP4F2 (0.42) | IGF1RALOX15CYP4F2CYP4A11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2000855-B1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | RICOH CO LTD (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | RICOH COMPANY, LTD. | 2008-12-11 | — | — | US | disclosed |
| EP-2000855-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | Ricoh Company, Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | KDM1A, C9, JMJD6 | IGF1R 349/4885ALOX15 2176/4885RARB 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.