SCHEMBL12679109

SCHEMBL12679109

Cc1ccc(-c2ccc(N(c3ccc(CCO)cc3)c3ccc(CCO)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP4F2 P78329 2/20 0.42
▸ CYP4A11 Q02928 2/20 0.42
▸ CA2 P00918 1/20 0.42
▸ CYP1A2 P05177 1/20 0.41
▸ CYP2A6 P11509 1/20 0.41
▸ TAAR1 Q96RJ0 1/20 0.41
▸ HRH3 Q9Y5N1 1/20 0.39
▸ BACE1 P56817 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ IGF1R P08069 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ TRPV1 Q8NER1 1/20 0.35
▸ PTGES O14684 1/20 0.35
▸ ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2307510 1.00 CYP4F2 (0.42) CYP4F2CYP4A11CA2CYP1A2CYP2A6
SCHEMBL12679111 1.00 CYP4F2 (0.42) CYP4F2CYP4A11CA2CYP1A2CYP2A6
SCHEMBL9009517 0.94 CA2 (0.46) CYP4F2CYP4A11CA2CYP1A2CYP2A6
SCHEMBL15853471 0.94 CA2 (0.46) CYP4F2CYP4A11CA2CYP1A2CYP2A6
SCHEMBL2308541 0.89 IGF1R (0.42) CYP4A11CA2CYP1A2CYP2A6TAAR1
SCHEMBL2312551 0.89 S1PR1 (0.39) CYP4F2CYP4A11CA2CYP1A2CYP2A6
SCHEMBL15725304 0.88 CA2 (0.52) CYP4F2CYP4A11CA2CYP1A2CYP2A6
SCHEMBL2310186 0.88 IGF1R (0.45) CYP4F2CYP4A11CA2IGF1RALOX15
SCHEMBL2316061 0.87 BACE1 (0.37) CYP4F2CYP4A11CA2CYP1A2CYP2A6
SCHEMBL2307322 0.86 IGF1R (0.44) CYP4F2CYP4A11CA2IGF1RALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 — — US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 — — US disclosed
US-20100330475-A1 IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE BEARING MEMBER RICOH COMPANY LIMITED (JP) 2010-12-30 — — US disclosed
US-20100150606-A1 METHOD OF MANUFACTURING IMAGE BEARING MEMBER, IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-06-17 — — US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 — — US disclosed
Send feedback