Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23075318 | 0.82 | RIPK1 (0.64) | RIPK1 | |
| SCHEMBL25585078 | 0.79 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL23075162 | 0.78 | RIPK1 (0.43) | RIPK1 | |
| SCHEMBL26493256 | 0.78 | RIPK1 (0.76) | RIPK1 | |
| SCHEMBL26493090 | 0.78 | RIPK1 (0.76) | RIPK1 | |
| SCHEMBL26493254 | 0.78 | RIPK1 (0.76) | RIPK1 | |
| SCHEMBL23075150 | 0.77 | RIPK1 (0.80) | RIPK1 | |
| SCHEMBL23066803 | 0.77 | RIPK1 (0.80) | RIPK1 | |
| SCHEMBL23066801 | 0.77 | RIPK1 (0.80) | RIPK1 | |
| SCHEMBL23066792 | 0.77 | RIPK1 (0.77) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046407-A1 | RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | RIGEL PHARMACEUTICALS, INC. (US) | 2021-03-11 | — | — | WO | disclosed |