Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18052180 | 0.94 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL17920570 | 0.92 | ABCB1 (0.35) | ABCB1 | |
| SCHEMBL17920592 | 0.92 | ABCB1 (0.35) | ABCB1 | |
| SCHEMBL18463181 | 0.91 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL20457385 | 0.91 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL26469820 | 0.86 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL17915659 | 0.86 | ABCB1 (0.33) | ABCB1 | |
| SCHEMBL22145449 | 0.86 | ABCB1 (0.34) | ABCB1 | |
| SCHEMBL17921910 | 0.86 | ABCB1 (0.33) | ABCB1 | |
| SCHEMBL1709968 | 0.85 | ABCB1 (0.32) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210405060-A1 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | Revolution Medicines, Inc. | 2021-12-30 | — | — | US | disclosed |
| US-10948495-B2 | Methods and reagents for analyzing protein-protein interfaces | Revolution Medicines, Inc. (US) | 2021-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210405060-A1 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | FKBP8, PIN1, FKBP1A | ABCB1 3866/4885 |
| US-10948495-B2 | Methods and reagents for analyzing protein-protein interfaces | FKBP8, PIN1, FKBP1A | ABCB1 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.