Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23846278 | 0.84 | HTR2A (0.37) | HTR2AHRH1PRMT3CARM1PRMT6 | |
| SCHEMBL27254422 | 0.81 | — | — | |
| SCHEMBL21026079 | 0.77 | HTR2A (0.33) | HTR2AHRH1 | |
| SCHEMBL20676375 | 0.77 | HTR2A (0.33) | HTR2AHRH1 | |
| SCHEMBL17133284 | 0.75 | DNM1 (0.35) | HTR2AHRH1 | |
| SCHEMBL19979728 | 0.75 | HTR2A (0.32) | HTR2AHRH1 | |
| SCHEMBL15027049 | 0.70 | — | — | |
| SCHEMBL17538539 | 0.70 | — | — | |
| SCHEMBL20414743 | 0.69 | — | — | |
| SCHEMBL18400897 | 0.68 | HTR2A (0.31) | HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947201-B2 | Certain chemical entities, compositions, and methods | NEUPHARMA, INC. (US) | 2021-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947201-B2 | Certain chemical entities, compositions, and methods | BRAF, PIK3CA, PLK1 | HTR2A 3472/4885HRH1 3177/4885PRMT3 1330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.