Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23846278 | 0.84 | HTR2A (0.37) | HTR2AHRH1 | |
| SCHEMBL20676375 | 0.77 | HTR2A (0.33) | HTR2AHRH1 | |
| SCHEMBL21026079 | 0.77 | HTR2A (0.33) | HTR2AHRH1 | |
| SCHEMBL23095438 | 0.75 | HTR2A (0.32) | HTR2AHRH1 | |
| SCHEMBL17133284 | 0.75 | DNM1 (0.35) | HTR2AHRH1 | |
| SCHEMBL13006571 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL25005649 | 0.74 | ANPEP (0.36) | — | |
| SCHEMBL19890029 | 0.74 | HTR2A (0.34) | HTR2AHRH1 | |
| SCHEMBL141055 | 0.72 | — | — | |
| SCHEMBL9989406 | 0.71 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053302-A1 | MACROCYCLIC COMPOUNDS FOR THE INHIBITION OF INDOLEAMINE-2,3-DIOXYGENASE ACTIVITY AND USE THEREOF | ENSEMBLE THERAPEUTICS CORPORATION (US) | 2018-03-22 | — | — | WO | disclosed |