Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 6/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097701 | 0.90 | KCNH2 (0.70) | KCNH2DRD2DRD3HTR1A | |
| SCHEMBL2021505 | 0.82 | KCNH2 (0.83) | KCNH2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2021501 | 0.82 | KCNH2 (0.83) | KCNH2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2021499 | 0.82 | KCNH2 (0.83) | KCNH2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10745044 | 0.81 | DRD2 (0.80) | DRD2DRD3HTR1AKDM4EALDH1A1 | |
| SCHEMBL23097784 | 0.80 | DRD2 (0.61) | KCNH2DRD2DRD3 | |
| SCHEMBL10518689 | 0.78 | SIGMAR1 (0.62) | DRD2DRD3HTR1A | |
| SCHEMBL23097637 | 0.75 | DRD2 (0.58) | KCNH2DRD2DRD3HTR1A | |
| SCHEMBL19048005 | 0.75 | KDM1A (0.63) | KCNH2DRD2 | |
| SCHEMBL20372647 | 0.75 | HRH3 (0.71) | KCNH2DRD2DRD3HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170334-B1 | NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION | UNIV EMORY (US) | 2021-03-17 | — | — | EP | disclosed |