Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545909 | 0.81 | TSHR (0.39) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL9056681 | 0.80 | TSHR (0.55) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL21661212 | 0.78 | TSHR (0.68) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL8894370 | 0.75 | NOS2 (0.38) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL210387 | 0.75 | NOS2 (0.49) | TSHRALDH1A1 | |
| SCHEMBL16326649 | 0.75 | TSHR (0.38) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL210388 | 0.75 | NOS2 (0.49) | TSHRALDH1A1 | |
| SCHEMBL3928876 | 0.75 | NOS2 (0.49) | TSHRALDH1A1 | |
| SCHEMBL13402460 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL7265297 | 0.74 | TSHR (0.36) | TSHRALDH1A1KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217995-A1 | COMPOSITIONS FOR CHEMICAL SYNTHESIS OF PEPTIDES | SEDERMA (FR) | 2024-07-04 | — | — | US | disclosed |
| US-20240217995-A1 | COMPOSITIONS FOR CHEMICAL SYNTHESIS OF PEPTIDES | SEDERMA (FR) | 2024-07-04 | — | — | US | disclosed |
| US-12024537-B2 | Compositions and methods for chemical synthesis | SEDERMA (FR) | 2024-07-02 | — | — | US | disclosed |
| US-20210079036-A1 | COMPOSITIONS AND METHODS FOR CHEMICAL SYNTHESIS | GAP PEPTIDES LLC (US) | 2021-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024537-B2 | Compositions and methods for chemical synthesis | NGLY1, DNPEP, HM13 | TSHR 3502/4885ALDH1A1 4375/4885KDM4E 3558/4885 |
| US-20210079036-A1 | COMPOSITIONS AND METHODS FOR CHEMICAL SYNTHESIS | NGLY1, DNPEP, HM13 | TSHR 3502/4885ALDH1A1 4375/4885KDM4E 3558/4885 |
| US-20240217995-A1 | COMPOSITIONS FOR CHEMICAL SYNTHESIS OF PEPTIDES | PTMS, DNPEP, ANPEP | TSHR 2244/4885ALDH1A1 4405/4885KDM4E 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.