Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ADH1B | P00325 | 4/20 | 0.45 |
| ▸ | ADH1A | P07327 | 4/20 | 0.45 |
| ▸ | ADH7 | P40394 | 3/20 | 0.45 |
| ▸ | ADH1C | P00326 | 3/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25905661 | 0.96 | BLM (0.47) | LTA4HBLMADH1BADH1AADH7 | |
| SCHEMBL17017527 | 0.88 | GABRR1 (0.52) | LTA4HBLMADH1BADH1AADH7 | |
| SCHEMBL7179523 | 0.80 | BLM (0.65) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL16330413 | 0.80 | BLM (0.65) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL9910890 | 0.79 | LTA4H (0.50) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL23981544 | 0.79 | LTA4H (0.50) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL9333340 | 0.79 | LTA4H (0.50) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL3587010 | 0.78 | BLM (0.50) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL18272798 | 0.78 | ACE2 (0.52) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL9001608 | 0.78 | ACE2 (0.64) | LTA4HBLMACE2GABRR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11872262-B2 | Means and methods for treating bacterial infections | VIB VZW (BE) | 2024-01-16 | — | — | US | disclosed |
| US-11872262-B2 | Means and methods for treating bacterial infections | VIB VZW (BE) | 2024-01-16 | — | — | US | disclosed |
| US-20210077563-A1 | Means and Methods for Treating Bacterial Infections | VIB VZW (BE) | 2021-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210077563-A1 | Means and Methods for Treating Bacterial Infections | VIP, MMP8, SLC11A2 | LTA4H 915/4885BLM 1975/4885ADH1B 4221/4885 |
| US-11872262-B2 | Means and methods for treating bacterial infections | VIP, MMP8, SLC11A2 | LTA4H 915/4885BLM 1975/4885ADH1B 4221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.