Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23099416 | 0.85 | BCHE (0.42) | BCHEMALT1PDE3BPDE3ACCNC | |
| SCHEMBL4897023 | 0.82 | BCHE (0.48) | EGLN2BCHEMALT1DDB1CRBN | |
| SCHEMBL29582812 | 0.82 | EGLN2 (0.53) | EGLN2GPR119TRPA1MAP2K1 | |
| SCHEMBL13862132 | 0.81 | CDK2 (0.46) | CDK2BCHEMALT1PDE3BPDE3A | |
| SCHEMBL23099475 | 0.80 | CDK2 (0.44) | CDK2BCHEMALT1PDE3BPDE3A | |
| SCHEMBL580876 | 0.79 | STK17B (0.49) | CCNCCDK8MGLL | |
| SCHEMBL17623716 | 0.79 | IRAK4 (0.43) | EGLN2MGLL | |
| SCHEMBL16935645 | 0.79 | FFAR1 (0.46) | EGLN2GPR119TRPA1AAK1CTSS | |
| SCHEMBL27299015 | 0.77 | CDK2 (0.39) | CDK2EGLN2BCHEMALT1PDE3B | |
| SCHEMBL25496774 | 0.77 | MEN1 (0.45) | EGLN2CCNCCDK8TRPA1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021048342-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-03-18 | — | — | WO | disclosed |