Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | STK17B | O94768 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27298994 | 0.83 | CDK2 (0.41) | CDK2BCHEPDE3BPDE3AMALT1 | |
| SCHEMBL23099474 | 0.77 | CDK2 (0.43) | CDK2TRPA1BCHEPDE3BPDE3A | |
| SCHEMBL25513515 | 0.76 | PDE3B (0.45) | CDK2BCHEPDE3BPDE3AMALT1 | |
| SCHEMBL16703087 | 0.76 | CDK2 (0.46) | CDK2BCHEPDE3BPDE3AMALT1 | |
| SCHEMBL21710418 | 0.75 | MALT1 (0.40) | CDK2TRPA1BCHEPDE3BPDE3A | |
| SCHEMBL21710422 | 0.74 | AAK1 (0.46) | CDK2BCHEPDE3BPDE3AMALT1 | |
| SCHEMBL20076225 | 0.73 | TRPA1 (0.42) | CDK2TRPA1BCHEPDE3BPDE3A | |
| SCHEMBL6510593 | 0.73 | KDM4E (0.61) | BCHEMALT1KDM4EGAAMAPT | |
| SCHEMBL3360033 | 0.72 | STK17B (0.46) | BCHEMALT1STK17BSTK17A | |
| SCHEMBL5356658 | 0.72 | GAA (0.49) | KDM4EGAAMAPTRXFP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023249968-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING PYRIDO[2,3-DJPYRIMIDIN-7(8H)-ONE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |