Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770310 | 0.85 | ALDH1A1 (0.53) | GAAALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL23099631 | 0.77 | CYP2C9 (0.39) | GAAALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL3974420 | 0.77 | ALDH1A1 (0.69) | GAAALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL23109304 | 0.73 | ALDH1A1 (0.53) | GAAALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL21527333 | 0.72 | ALDH1A1 (0.56) | GAAALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL12295206 | 0.72 | CYP2C9 (0.67) | GAAALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL23099496 | 0.71 | CYP2C9 (0.38) | GAAALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL10431662 | 0.71 | ALDH1A1 (0.55) | GAAALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL23099499 | 0.71 | MTNR1B (0.44) | GAAALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL23092198 | 0.70 | POLB (0.47) | GAAALDH1A1POLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021048342-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-03-18 | — | — | WO | disclosed |