Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23099404 | 0.88 | KDM4E (0.39) | KDM4ERAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL22279584 | 0.83 | RAB9A (0.65) | KDM4ERAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL12295206 | 0.81 | CYP2C9 (0.67) | KDM4ERAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL23099627 | 0.81 | NPC1 (0.50) | KDM4ERAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL23197396 | 0.80 | RAB9A (0.49) | KDM4ERAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL23099502 | 0.80 | KDM4E (0.49) | KDM4ERAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL18629888 | 0.78 | SLC22A12 (0.37) | KDM4ECYP1A2CYP2C9CYP2C19MAPK1 | |
| SCHEMBL23099634 | 0.78 | RAB9A (0.47) | KDM4ERAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL1355437 | 0.76 | MAPK1 (0.43) | KDM4ERAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL12295364 | 0.76 | MAPK1 (0.75) | KDM4ERAB9ANPC1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021048342-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-03-18 | — | — | WO | disclosed |