Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | AGER | Q15109 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14008052 | 0.89 | NPY5R (0.52) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL8615898 | 0.89 | NPY5R (0.52) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL14008053 | 0.89 | NPY5R (0.52) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL23099904 | 0.82 | ATM (0.44) | LIMK2AGERRAB9AMTNR1APPARG | |
| SCHEMBL11588617 | 0.77 | ADRA2B (0.61) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL7636285 | 0.76 | NPY5R (0.55) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL14008051 | 0.76 | NPY5R (0.55) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL7636288 | 0.76 | NPY5R (0.55) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL13034674 | 0.76 | HDAC4 (0.49) | RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL5644792 | 0.75 | LIMK2 (0.70) | LIMK2AGERHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050992-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. (US) | 2021-03-18 | — | — | WO | disclosed |