SCHEMBL2310

SCHEMBL2310

Cc1ccc(C(=O)Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
CES2 O00748 3/20 0.62
CES1 P23141 3/20 0.62
LMNA P02545 3/20 0.62
SMN1; SMN2 Q16637 4/20 0.59
KMT2A Q03164 4/20 0.54
HTT P42858 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
HPGD P15428 3/20 0.54
MEN1 O00255 3/20 0.54
PKM P14618 2/20 0.54
ATM Q13315 2/20 0.54
NLRP1 Q9C000 1/20 0.54
GAA P10253 1/20 0.54
NTSR1 P30989 1/20 0.54
SRD5A2 P31213 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
GSK3B P49841 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5637913 1.00 ALDH1A1 (0.62) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL6668626 0.93 ALDH1A1 (0.54) ALDH1A1CES2CES1LMNASMN1; SMN2
Dimethylamine SCHEMBL6797110 0.93 ALDH1A1 (0.54) ALDH1A1CES2CES1LMNASMN1; SMN2
Dimethylamine SCHEMBL9836167 0.91 ALDH1A1 (0.52) ALDH1A1CES2CES1LMNASMN1; SMN2
Benzoyl Chloride SCHEMBL1397148 0.91 CES2 (0.68) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL27554623 0.89 ALDH1A1 (0.50) ALDH1A1CES2CES1LMNASMN1; SMN2
Toluene SCHEMBL29163900 0.87 CES2 (0.58) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL14984235 0.87 MAPT (0.60) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL29196067 0.87 ALDH1A1 (0.48) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL7314075 0.87 HPGD (0.54) ALDH1A1CES2CES1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4495 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284203-B Tanshinone IIA C-1 position esterified derivative and preparation method and application thereof 郑州大学 2025-06-10 CN claimed
CN-119874597-A Preparation method of medical intermediate 百泰生物药业有限公司 2025-04-25 CN claimed
CN-119552361-A Novel method for efficiently preparing polysulfone resin 河南润巍新材料有限公司 2025-03-04 CN claimed
CN-119462646-A Substituted tetrahydro-beta-carboline derivative, synthesis method and application thereof 江苏科技大学 2025-02-18 CN claimed
EP-4229005-B1 TETRAAZADODECANE BASED CHELATING AGENTS FOR SEPARATION OF RARE EARTH ELEMENTS AND METHOD THEREFOR USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2024-12-25 EP claimed
CN-119176937-A Modified aramid fiber diaphragm coating slurry, battery diaphragm and preparation method of battery diaphragm 烟台泰和新材高分子新材料研究院有限公司 2024-12-24 CN claimed
CN-116410106-B Benzamide HBV capsid protein inhibitor and preparation method and application thereof 山东第二医科大学 2024-12-06 CN claimed
CN-119019420-A Synthesis method of cephalosporin intermediate YGH 广东立国制药有限公司 2024-11-26 CN claimed
CN-118955593-A Preparation method of 2' -alkoxy adenosine analogue 杭州中美华东制药有限公司 2024-11-15 CN claimed
CN-118914404-A 2-Methyl-L-leucine hydrochloride and enantiomer detection method thereof 佛山奕安赛医药科技有限公司 2024-11-08 CN claimed
US-6124512-A HETEROGENEOUS CATALYST. OCCIDENTAL CHEMICAL CORPORATION (US) 2000-09-26 US claimed
EP-0561568-A1 Polyisocyanate composition DOW MITSUBISHI KASEI LIMITED (JP) 1993-09-22 EP claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
EP-0158000-B1 REGIO AND OPTICAL ISOMERS OF IMIDAZOLINYL TOLUIC ACIDS, ESTERS AND SALTS, THEIR METHOD OF PREPARATION AND THEIR USE AS HERBICIDAL AGENTS AMERICAN CYANAMID COMPANY (US) 1991-06-19 EP claimed
US-4980485-A Method of manufacturing optically-active periplanone-b JAPAN TOBACCO INC. (JP) 1990-12-25 US claimed
EP-0188099-B1 POLYMERIZATION CATALYST, PRODUCTION AND USE EXXON RESEARCH AND ENGINEERING COMPANY (US) 1989-08-30 EP claimed
US-4634751-A Polymerization catalyst, production and use EXXON RESEARCH & ENGINEERING CO. (US) 1987-01-06 US claimed
EP-0188099-A1 Polymerization catalyst, production and use EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-07-23 EP claimed
US-4579835-A VANDIUM, ALUMINUM, ACYL HALIDE COMPONENTS EXXON RESEARCH & ENGINEERING CO. (US) 1986-04-01 US claimed
EP-0158000-A1 Regio and optical isomers of imidazolinyl toluic acids, esters and salts, their method of preparation and their use as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1985-10-16 EP claimed