SCHEMBL231005

SCHEMBL231005

C[Si](C)(C)Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.56
TP53 P04637 1/20 0.48
CALM1 P0DP23 1/20 0.45
TSHR P16473 4/20 0.42
ALDH1A1 P00352 4/20 0.42
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
IDO1 P14902 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
TRPA1 O75762 1/20 0.41
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
MAOB P27338 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19979090 0.85 ESR1 (0.54) ESR1TSHRALDH1A1IDO1HPGD
SCHEMBL3949041 0.84 ESR1 (0.74) ESR1ALDH1A1IDO1
SCHEMBL6506604 0.84 TSHR (0.62) ESR1TSHRALDH1A1IDO1KDM4E
SCHEMBL16378246 0.82 TP53 (0.48) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL1107767 0.82 TP53 (0.48) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL19738594 0.81 ESR1 (0.50) ESR1TP53NR1H2NR1H3LOXL2
SCHEMBL9350315 0.79 ESR1 (0.48) ESR1TP53TSHRALDH1A1KDM4E
SCHEMBL2098666 0.78 TP53 (0.43) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL8381659 0.78 TP53 (0.43) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL9224737 0.78 TP53 (0.43) TP53CALM1TSHRALDH1A1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4204219-B1 PARTIAL COATING OF INTRAOCULAR LENSES USING SPATIAL ALD AMO GRONINGEN BV (NL) 2026-05-06 EP claimed
US-12522920-B2 Partial coating of intraocular lenses using spatial atomic layer deposition AMO GRONINGEN B.V. (NL) 2026-01-13 US claimed
CN-119612974-A Method for enhancing interface bonding strength of insulating substrate and metal layer 广东工业大学 2025-03-14 CN claimed
CN-114989031-B Preparation method for synthesizing unsaturated amide by carbon dioxide and alkyne 湖南工程学院 2024-08-20 CN claimed
CN-118221495-A Method for shortening effective residence time of ethylene oligomerization to serial linear alpha-olefin 中国石油天然气股份有限公司 2024-06-21 CN claimed
CN-115304441-B Preparation method of amide synthesized by carbon dioxide and olefin 湖南工程学院 2024-03-26 CN claimed
CN-116003360-B Preparation method for synthesizing orange compounds from carbon dioxide and alkyne 湖南工程学院 2024-01-23 CN claimed
CN-115403465-B Preparation method for synthesizing organic carboxylic ester by carbon dioxide and olefin 湖南工程学院 2023-08-18 CN claimed
EP-4204219-A1 PARTIAL COATING OF INTRAOCULAR LENSES USING SPATIAL ALD Amo Groningen B.V. (NL) 2023-07-05 EP claimed
CN-116003360-A Preparation method for synthesizing orange compounds from carbon dioxide and alkyne 湖南工程学院 2023-04-25 CN claimed
WO-2005019503-A2 SUB-MICRON-SCALE PATTERNING METHOD AND SYSTEM NANOOPTO CORPORATION (US) 2005-03-03 WO claimed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US claimed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US claimed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US claimed
US-6436824-B1 Low dielectric constant materials for copper damascene CHARTERED SEMICONDUCTOR MANUFACTURING LTD. (SG) 2002-08-20 US claimed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP claimed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO claimed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP claimed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO claimed
EP-0363284-B1 Use of peptidase inhibitors for the preparation of medicaments useful for the treatment of strokes MERRELL PHARMA INC (US) 1997-05-14 EP claimed