Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.39 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430043 | 0.91 | ESR1 (0.62) | TSHRESR1IDO1TDP1L3MBTL1 | |
| SCHEMBL6507494 | 0.87 | L3MBTL1 (0.49) | TSHRESR1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL6508968 | 0.84 | L3MBTL1 (0.57) | TSHRESR1IDO1TDP1L3MBTL1 | |
| SCHEMBL231005 | 0.84 | ESR1 (0.56) | TSHRESR1IDO1TDP1ALDH1A1 | |
| SCHEMBL9795394 | 0.82 | TSHR (0.94) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL27380 | 0.79 | TSHR (1.00) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL5311581 | 0.79 | TSHR (1.00) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL17284082 | 0.78 | TSHR (0.61) | TSHRIDO1TDP1L3MBTL1AGXT | |
| Propane SCHEMBL11584021 | 0.77 | TSHR (0.83) | TSHRIDO1TDP1L3MBTL1AGXT | |
| SCHEMBL9491202 | 0.77 | TSHR (0.94) | TSHRIDO1AGXTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100329-A1 | NOVEL PROTECTING REAGENTS, PROTECTING GROUPS AND METHODS OF FORMING AND USING THE SAME | THE UNIVERSITY OF MISSISSIPI (US) | 2005-10-27 | — | — | WO | disclosed |