SCHEMBL1107767

SCHEMBL1107767

C[Si](C)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
CALM1 P0DP23 1/20 0.45
TSHR P16473 4/20 0.42
ALDH1A1 P00352 4/20 0.42
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
IDO1 P14902 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
TRPA1 O75762 1/20 0.41
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
MAOB P27338 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1271761 0.87 TP53 (0.42) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL14838179 0.87 TP53 (0.48) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL5514135 0.85 TSHR (0.46) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL9076841 0.85 TP53 (0.40) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL9075995 0.85 LOXL2 (0.46) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL8970493 0.85 TSHR (0.46) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL8969428 0.85 ALDH1A1 (0.44) TP53CALM1TSHRALDH1A1NR1H2
Hydrochloric Acid SCHEMBL9074421 0.83 LOXL2 (0.44) TP53CALM1NR1H2NR1H3LOXL2
SCHEMBL16378246 0.82 TP53 (0.48) TP53CALM1TSHRALDH1A1NR1H2
SCHEMBL231005 0.82 ESR1 (0.56) TP53CALM1TSHRALDH1A1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101018815-A Multiple catalyst and reactor system for olefin polymerization and polymers produced thereby EXXONMOBIL CHEM PATENTS INC (US) 2007-08-15 CN claimed
EP-0067066-B2 Dry-developing resist composition FUJITSU LTD (JP) 1994-01-12 EP claimed
EP-0067066-B1 DRY-DEVELOPING RESIST COMPOSITION FUJITSU LIMITED (JP) 1985-12-18 EP claimed
EP-0067067-B1 DRY-DEVELOPING NEGATIVE RESIST COMPOSITION FUJITSU LIMITED (JP) 1985-09-25 EP claimed
US-4481279-A Dry-developing resist composition FUJITSU LIMITED (JP) 1984-11-06 US claimed
US-4464455-A Dry-developing negative resist composition FUJITSU LIMITED (JP) 1984-08-07 US claimed
EP-0067066-A2 Dry-developing resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
EP-0067067-A2 Dry-developing negative resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
WO-2022054912-A1 RESIN COMPOSITION, CURED PRODUCT AND MANUFACTURING METHOD THEREFOR, AND LAMINATE 三菱ケミカル株式会社 2022-03-17 WO disclosed
US-11038145-B2 Laminated film and process for manufacturing the same, as well as method for analyzing laminated film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-15 US disclosed
EP-3135745-B1 SEMICONDUCTOR NANOPARTICLE ASSEMBLY AND METHOD FOR PRODUCING SAME KONICA MINOLTA INC (JP) 2021-03-10 EP disclosed
CN-107331784-B Laminated film and method for producing same 住友化学株式会社 2020-11-27 CN disclosed
CN-107955159-B Silicon-containing main chain arylethernitrile copolymer and preparation method thereof 徐州工程学院 2020-11-20 CN disclosed
CN-107955157-B Crosslinkable silicon-containing main chain arylethernitrile copolymer and preparation method thereof 徐州工程学院 2020-11-20 CN disclosed
EP-0067067-B1 DRY-DEVELOPING NEGATIVE RESIST COMPOSITION FUJITSU LIMITED (JP) 1985-09-25 EP disclosed
US-4481279-A Dry-developing resist composition FUJITSU LIMITED (JP) 1984-11-06 US disclosed
US-4464455-A Dry-developing negative resist composition FUJITSU LIMITED (JP) 1984-08-07 US disclosed
EP-0067066-A2 Dry-developing resist composition FUJITSU LIMITED (JP) 1982-12-15 EP disclosed
EP-0067067-A2 Dry-developing negative resist composition FUJITSU LIMITED (JP) 1982-12-15 EP disclosed
US-4274996-A SILANE COMPOUNDS PHILLIPS PETROLEUM COMPANY (US) 1981-06-23 US disclosed