Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 15/20 | 0.67 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.51 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.51 |
| ▸ | RHOC | P08134 | 1/20 | 0.48 |
| ▸ | RHOA | P61586 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743141 | 0.92 | LTC4S (0.63) | LTC4SRHOCRHOA | |
| SCHEMBL232016 | 0.92 | LTC4S (0.61) | LTC4SKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL2743143 | 0.89 | LTC4S (0.52) | LTC4S | |
| SCHEMBL232068 | 0.89 | LTC4S (0.56) | LTC4S | |
| SCHEMBL2743144 | 0.85 | LTC4S (0.57) | LTC4SKCNQ3KCNQ2 | |
| SCHEMBL10206534 | 0.85 | LTC4S (0.78) | LTC4S | |
| SCHEMBL250983 | 0.84 | LTC4S (0.56) | LTC4S | |
| SCHEMBL234665 | 0.84 | LTC4S (0.56) | LTC4S | |
| SCHEMBL231537 | 0.83 | P4HTM (0.57) | LTC4S | |
| SCHEMBL2755466 | 0.80 | LTC4S (1.00) | LTC4S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | LTC4S 1/4885KCNQ3 1524/4885KCNQ2 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.