Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2309012 | 0.92 | TSHR (0.41) | ALDH1A1CYP2C19CYP3A4MAPTTDP1 | |
| SCHEMBL2204995 | 0.90 | ALDH1A1 (0.48) | ALDH1A1CYP2C19L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL172867 | 0.82 | HTT (0.52) | ALDH1A1CYP2C19L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL8944029 | 0.82 | HTT (0.52) | ALDH1A1CYP2C19L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL14732541 | 0.82 | HTT (0.52) | ALDH1A1CYP2C19L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL23254850 | 0.82 | HTT (0.52) | ALDH1A1CYP2C19L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL14732511 | 0.82 | HTT (0.52) | ALDH1A1CYP2C19L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL15729985 | 0.82 | HTT (0.52) | ALDH1A1CYP2C19L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL12154508 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP2C19L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL43023 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP2C19L3MBTL1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2000855-B1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | RICOH CO LTD (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | RICOH COMPANY, LTD. | 2008-12-11 | — | — | US | disclosed |
| EP-2000855-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | Ricoh Company, Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | KDM1A, C9, JMJD6 | ALDH1A1 1243/4885CYP2C19 980/4885L3MBTL1 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.