Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23102408 | 0.84 | DUT (0.41) | DUT | |
| SCHEMBL23102584 | 0.83 | JAK2 (0.37) | JAK2BTK | |
| SCHEMBL20805166 | 0.71 | DUT (0.41) | DUTJAK2BTK | |
| SCHEMBL26636093 | 0.68 | MAPT (0.34) | DUTJAK2BTK | |
| SCHEMBL23102577 | 0.66 | JAK2 (0.34) | JAK2BTK | |
| SCHEMBL23108309 | 0.65 | TNF (0.39) | — | |
| SCHEMBL23102583 | 0.65 | USP2 (0.35) | — | |
| SCHEMBL23108300 | 0.65 | TNF (0.41) | — | |
| SCHEMBL23102416 | 0.64 | TP53 (0.31) | — | |
| SCHEMBL30922686 | 0.63 | JAK2 (0.34) | DUTJAK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047556-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME AND USE THEREOF | 上海长森药业有限公司 | 2021-03-18 | — | — | WO | disclosed |