Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23102420 | 0.82 | TP53 (0.35) | TP53TOP2AMAPTS1PR1 | |
| SCHEMBL23102408 | 0.79 | DUT (0.41) | — | |
| SCHEMBL23102479 | 0.78 | PIK3R1 (0.36) | TP53TOP2AMAPT | |
| SCHEMBL23102423 | 0.76 | GRM2 (0.31) | — | |
| SCHEMBL23102583 | 0.74 | USP2 (0.35) | TP53TOP2AMAPTS1PR1 | |
| SCHEMBL23108686 | 0.72 | TOP2A (0.37) | TP53TOP2AMAPT | |
| SCHEMBL23102698 | 0.71 | — | — | |
| SCHEMBL23108309 | 0.71 | TNF (0.39) | TP53TOP2AMAPT | |
| SCHEMBL23102409 | 0.69 | C1R (0.40) | TP53TOP2AMAPTS1PR1 | |
| SCHEMBL23102594 | 0.67 | TP53 (0.33) | TP53TOP2AMAPTS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047556-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME AND USE THEREOF | 上海长森药业有限公司 | 2021-03-18 | — | — | WO | disclosed |