Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23102546 | 0.83 | SMN1; SMN2 (0.42) | PDCD1CD274KDM4EMAPTTDP1 | |
| SCHEMBL23102583 | 0.77 | USP2 (0.35) | PDCD1CD274KDM4ETP53MAPT | |
| SCHEMBL23102475 | 0.76 | NPSR1 (0.33) | RECQLALDH1A1PKMNPSR1 | |
| SCHEMBL23102534 | 0.71 | MAOA (0.34) | PDCD1CD274MAOAMAOB | |
| SCHEMBL23108521 | 0.71 | MAOA (0.36) | PDCD1CD274MAOAMAOB | |
| SCHEMBL23108520 | 0.70 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL23102594 | 0.69 | TP53 (0.33) | PDCD1CD274KDM4ETP53MAPT | |
| SCHEMBL23108301 | 0.69 | KDM1A (0.33) | MAOAMAOB | |
| SCHEMBL23102415 | 0.68 | PDCD1 (0.37) | PDCD1CD274KDM4EMEN1TP53 | |
| SCHEMBL1238531 | 0.68 | TNF (0.38) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047555-A1 | PREPARATION OF AROMATIC HETEROCYCLIC DERIVATIVE AS IMMUNOMODULATOR AND APPLICATION THEREOF | 上海长森药业有限公司 | 2021-03-18 | — | — | WO | disclosed |
| WO-2021047556-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME AND USE THEREOF | 上海长森药业有限公司 | 2021-03-18 | — | — | WO | disclosed |