SCHEMBL2310342

SCHEMBL2310342

Cc1ccc(N(c2ccccc2)c2c(C)cc(C)cc2C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.42
ALDH1A1 P00352 3/20 0.40
TSHR P16473 3/20 0.40
CYP1A2 P05177 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.40
ALOX12 P18054 1/20 0.40
ACHE P22303 1/20 0.40
APP P05067 1/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
CYP2A6 P11509 1/20 0.38
CRHR1 P34998 1/20 0.37
RAPGEF4 Q8WZA2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1115692 0.96 L3MBTL1 (0.43) CYP2C19ALDH1A1TSHRCYP1A2L3MBTL1
SCHEMBL3477723 0.94 CYP1A2 (0.41) CYP2C19ALDH1A1TSHRCYP1A2L3MBTL1
SCHEMBL682063 0.91 ALDH1A1 (0.46) CYP2C19ALDH1A1TSHRCYP1A2CYP3A4
SCHEMBL12018763 0.91 ALDH1A1 (0.46) CYP2C19ALDH1A1TSHRCYP1A2CYP3A4
SCHEMBL19241177 0.90 MEN1 (0.40) CYP2C19ALDH1A1TSHRL3MBTL1KDM4E
SCHEMBL13949227 0.90 ALDH1A1 (0.38) CYP2C19ALDH1A1TSHRCYP1A2L3MBTL1
SCHEMBL9244552 0.90 ALDH1A1 (0.39) CYP2C19ALDH1A1TSHRCYP1A2L3MBTL1
SCHEMBL22550359 0.89 CYP1A2 (0.41) CYP2C19ALDH1A1TSHRCYP1A2L3MBTL1
SCHEMBL13197770 0.87 ALDH1A1 (0.42) CYP2C19ALDH1A1TSHRCYP1A2CYP3A4
SCHEMBL12313740 0.87 ALDH1A1 (0.42) CYP2C19ALDH1A1TSHRCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
EP-2000855-B1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH CO LTD (JP) 2011-08-03 EP disclosed
US-20110059393-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-03-10 US disclosed
US-20110059393-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-03-10 US disclosed
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed
EP-2000855-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge Ricoh Company, Ltd. (JP) 2008-12-10 EP disclosed
US-7241543-B2 Image forming method, a photoreceptor used for the apparatus, and an image forming unit KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-10 US disclosed
US-7241543-B2 Image forming method, a photoreceptor used for the apparatus, and an image forming unit KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-10 US disclosed
US-7238457-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-03 US disclosed
US-7238457-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-03 US disclosed
US-7175954-B2 Electrophotographic photoreceptor KONICA MINOLTA HOLDINGS, INC. (JP) 2007-02-13 US disclosed
US-7175954-B2 Electrophotographic photoreceptor KONICA MINOLTA HOLDINGS, INC. (JP) 2007-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 CYP2C19 980/4885ALDH1A1 1243/4885TSHR 4581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.