Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.39 |
| ▸ | NPY4R | P50391 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23330252 | 0.99 | SIRT2 (0.40) | SIRT2SIRT1SIRT5SIRT3NPY4R | |
| SCHEMBL23106472 | 0.99 | SIRT2 (0.40) | SIRT2SIRT1SIRT5SIRT3NPY4R | |
| SCHEMBL22138818 | 0.93 | SIRT2 (0.41) | SIRT2SIRT1SIRT5SIRT3NPY4R | |
| SCHEMBL20841069 | 0.93 | SIRT2 (0.41) | SIRT2SIRT1SIRT5SIRT3NPY4R | |
| SCHEMBL18911016 | 0.93 | SIRT2 (0.41) | SIRT2SIRT1SIRT5SIRT3NPY4R | |
| SCHEMBL23789221 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT5SIRT3NPY4R | |
| SCHEMBL21568762 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT5SIRT3NPY4R | |
| SCHEMBL18908995 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT5SIRT3NPY4R | |
| SCHEMBL19046262 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT5SIRT3NPY4R | |
| SCHEMBL20467874 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT5SIRT3NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130473-A1 | TGFßR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. | 2021-05-06 | — | — | US | disclosed |
| US-20210077632-A1 | Formulations of Benzazepine Conjugates and Uses Thereof | SILVERBACK THERAPEUTICS, INC. (US) | 2021-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210077632-A1 | Formulations of Benzazepine Conjugates and Uses Thereof | BDNF, FURIN, VGF | SIRT2 894/4885SIRT1 549/4885SIRT5 1008/4885 |
| US-20210130473-A1 | TGFßR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF | TGFBR2, ASGR1, TGFBR1 | SIRT2 1353/4885SIRT1 2240/4885SIRT5 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.