Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 7/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 2/20 | 0.39 |
| ▸ | MC3R | P41968 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1327577 | 0.99 | AGTR2 (0.52) | AGTR2DPP4DPP9DPP7SLC18A3 | |
| SCHEMBL2313050 | 0.97 | AGTR2 (0.49) | AGTR2DPP4DPP9DPP7L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1326549 | 0.96 | AGTR2 (0.48) | AGTR2DPP4DPP9DPP7L3MBTL1 | |
| SCHEMBL2313411 | 0.86 | DPP4 (0.53) | AGTR2DPP4DPP9DPP7SLC6A2 | |
| SCHEMBL2305093 | 0.86 | OPRM1 (0.51) | AGTR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1326542 | 0.85 | OPRM1 (0.50) | AGTR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1326773 | 0.85 | DPP4 (0.52) | AGTR2DPP4DPP9DPP7SLC6A2 | |
| SCHEMBL27936803 | 0.81 | SLC6A2 (0.42) | AGTR2SLC18A3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1327685 | 0.79 | DPP4 (0.56) | DPP4DPP9DPP7SLC6A2SLC6A4 | |
| SCHEMBL1326676 | 0.77 | MC4R (0.55) | MC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989174-B1 | SUBSTITUTED CYCLOHEXYLMETHYL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-08-03 | — | — | EP | claimed |
| JP-2009520720-A | — | — | 2009-05-28 | — | — | JP | claimed |
| EP-1989174-A1 | SUBSTITUTED CYCLOHEXYLMETHYL DERIVATIVES | Grünenthal GmbH (DE) | 2008-11-12 | — | — | EP | claimed |
| WO-2007079930-A1 | SUBSTITUTED CYCLOHEXYLMETHYL DERIVATIVES | Grünenthal GmbH (DE) | 2007-07-19 | — | — | WO | claimed |
| EP-1989174-B1 | SUBSTITUTED CYCLOHEXYLMETHYL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-08-03 | — | — | EP | disclosed |
| EP-1989174-A1 | SUBSTITUTED CYCLOHEXYLMETHYL DERIVATIVES | Grünenthal GmbH (DE) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007079930-A1 | SUBSTITUTED CYCLOHEXYLMETHYL DERIVATIVES | Grünenthal GmbH (DE) | 2007-07-19 | — | — | WO | disclosed |