Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208358 | 0.75 | MLYCD (0.41) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL23109987 | 0.73 | MEN1 (0.34) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL27848104 | 0.72 | KMT2A (0.36) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL23965315 | 0.72 | KMT2A (0.36) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL12013740 | 0.70 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL27950432 | 0.67 | TP53 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL22215185 | 0.65 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL4576097 | 0.65 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL2909351 | 0.64 | MGAM (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL27488643 | 0.64 | TSHR (0.43) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021049633-A1 | DRUG FOR CURATIVE THERAPY OF INTRACTABLE HEREDITARY RENAL ALPORT SYNDROME | 国立大学法人熊本大学 | 2021-03-18 | — | — | WO | disclosed |