Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848104 | 0.81 | KMT2A (0.36) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL23965315 | 0.81 | KMT2A (0.36) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL30063665 | 0.79 | DPP4 (0.43) | SLC1A1DPP4DPP9 | |
| SCHEMBL17208358 | 0.76 | MLYCD (0.41) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL12709894 | 0.76 | DPP4 (0.39) | SLC1A1TSHRDPP4DPP9 | |
| SCHEMBL23109985 | 0.73 | CA12 (0.31) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL26209588 | 0.73 | DPP4 (0.30) | DPP4DPP9 | |
| SCHEMBL6628997 | 0.72 | FAAH (0.38) | SLC1A1DPP4DPP9 | |
| SCHEMBL6629003 | 0.72 | FAAH (0.38) | SLC1A1DPP4DPP9 | |
| SCHEMBL10242493 | 0.71 | TSHR (0.42) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021049633-A1 | DRUG FOR CURATIVE THERAPY OF INTRACTABLE HEREDITARY RENAL ALPORT SYNDROME | 国立大学法人熊本大学 | 2021-03-18 | — | — | WO | disclosed |