Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307245 | 0.88 | ALDH1A1 (0.45) | TRPM4DHODHALDH1A1HSD17B10HIF1A | |
| SCHEMBL2311085 | 0.87 | CHEK1 (0.40) | TRPM4DHODHALDH1A1HSD17B10HIF1A | |
| SCHEMBL2308691 | 0.86 | CYP1A2 (0.42) | TRPM4DHODHALDH1A1HSD17B10HIF1A | |
| SCHEMBL2313600 | 0.86 | CYP1A2 (0.42) | TRPM4DHODHALDH1A1HSD17B10HIF1A | |
| SCHEMBL2309984 | 0.85 | ALDH1A1 (0.52) | TRPM4ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL2310494 | 0.85 | TDP1 (0.48) | TRPM4DHODHALDH1A1HSD17B10POLB | |
| SCHEMBL615452 | 0.85 | TRPM4 (0.54) | TRPM4DHODHALDH1A1HSD17B10HIF1A | |
| SCHEMBL2310404 | 0.84 | ALDH1A1 (0.56) | TRPM4ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL2310231 | 0.83 | CYP1A2 (0.43) | TRPM4DHODHALDH1A1HSD17B10HIF1A | |
| SCHEMBL2313386 | 0.83 | TDP1 (0.41) | TRPM4DHODHALDH1A1HIF1AHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970811-A2 | VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND A POLYAROMATIC HYDROCARBON | Chevron Oronite Company LLC (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149086-A2 | VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND A POLYAROMATIC HYDROCARBON | CHEVRON ORONITE COMPANY LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| US-7989517-B2 | Actinic ray curable composition, actinic ray curable ink, and image formation process employing the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2011-08-02 | — | — | US | disclosed |
| US-20070123600-A1 | ACTINIC RAY CURABLE COMPOSITION, ACTINIC RAY CURABLE INK, AND IMAGE FORMATION PROCESS EMPLOYING THE SAME | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-05-31 | — | — | US | disclosed |
| US-20030108892-A1 | Irradiation of pyrene and dimethyl aniline in water, forming labels for oligonucleotides, proteins, ceramics, transistors, semiconductors, insulators, or glass | THE UNIVERSITY OF MANCHESTER (GB) | 2003-06-12 | — | — | US | disclosed |
| EP-1242360-A2 | EXCIPLEXES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001046121-A2 | EXCIPLEXES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108892-A1 | Irradiation of pyrene and dimethyl aniline in water, forming labels for oligonucleotides, proteins, ceramics, transistors, semiconductors, insulators, or glass | MDM4, PHAX, DIMT1 | TRPM4 676/4885DHODH 2155/4885ALDH1A1 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.