Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 15/20 | 0.59 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.47 |
| ▸ | AURKA | O14965 | 3/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | PAK4 | O96013 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | IGF1R | P08069 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | PRKACA | P17612 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.47 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30684918 | 0.78 | MAPKAPK2 (0.57) | PTK2ROCK1 | |
| SCHEMBL30542313 | 0.77 | PTK2 (0.61) | PTK2FGFR1EGFRSRC | |
| SCHEMBL30219537 | 0.76 | PTK2 (0.48) | PTK2RPS6KA3AURKADAPK3JAK2 | |
| SCHEMBL28986295 | 0.76 | PTK2 (0.48) | PTK2RPS6KA3AURKADAPK3JAK2 | |
| SCHEMBL29277206 | 0.75 | AURKA (0.77) | RPS6KA3AURKAJAK2KDRJAK3 | |
| SCHEMBL12528978 | 0.75 | PTK2 (1.00) | PTK2RPS6KA3AURKADAPK3JAK2 | |
| SCHEMBL1655458 | 0.74 | PTK2 (0.56) | PTK2RPS6KA3AURKADAPK3JAK2 | |
| SCHEMBL4283794 | 0.74 | PTK2 (0.59) | PTK2RPS6KA3AURKADAPK3JAK2 | |
| SCHEMBL31052347 | 0.73 | L3MBTL1 (0.56) | FGFR1 | |
| SCHEMBL1655016 | 0.71 | STAT6 (0.58) | PTK2RPS6KA3AURKAJAK2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050700-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-03-18 | — | — | WO | disclosed |