Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.57 |
| ▸ | MAP3K14 | Q99558 | 16/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28986246 | 0.84 | MAPKAPK2 (0.57) | MAPKAPK2MAP3K14ROCK1 | |
| SCHEMBL26270373 | 0.83 | MAPKAPK2 (0.56) | MAPKAPK2MAP3K14DHFRROCK1 | |
| SCHEMBL28986278 | 0.80 | MAPKAPK2 (0.56) | MAPKAPK2MAP3K14 | |
| SCHEMBL30219552 | 0.80 | MAPKAPK2 (0.56) | MAPKAPK2MAP3K14 | |
| SCHEMBL23110509 | 0.78 | PTK2 (0.59) | PTK2ROCK1 | |
| SCHEMBL4978113 | 0.76 | XDH (0.48) | DHFR | |
| SCHEMBL28986210 | 0.74 | MAPKAPK2 (0.53) | MAPKAPK2MAP3K14 | |
| SCHEMBL30219596 | 0.74 | MAPKAPK2 (0.53) | MAPKAPK2MAP3K14PTK2 | |
| SCHEMBL28986263 | 0.74 | MAPKAPK2 (0.56) | MAPKAPK2MAP3K14 | |
| SCHEMBL30219632 | 0.74 | MAPKAPK2 (0.56) | MAPKAPK2MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263940-A | FGFR inhibitor, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2023-12-22 | — | — | CN | claimed |