Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23110777 | 0.79 | PTGS2 (0.64) | PTGS2 | |
| SCHEMBL29802782 | 0.78 | PTGS2 (0.54) | PTGS2 | |
| SCHEMBL23093418 | 0.78 | PTGS2 (0.54) | PTGS2 | |
| SCHEMBL23110506 | 0.78 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL23111082 | 0.76 | PTGS2 (0.69) | PTGS2 | |
| SCHEMBL23093261 | 0.69 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL8096151 | 0.68 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6513115 | 0.68 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8379250 | 0.67 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL8380751 | 0.67 | PTGS2 (0.69) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050700-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-03-18 | — | — | WO | disclosed |