Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23093418 | 1.00 | PTGS2 (0.54) | PTGS2MEN1NPC1POLBRAB9A | |
| SCHEMBL23110546 | 0.81 | MAPK14 (0.43) | PTGS2NPC1RAB9A | |
| SCHEMBL23110682 | 0.78 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL23111082 | 0.78 | PTGS2 (0.69) | PTGS2 | |
| SCHEMBL15730486 | 0.75 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL23110506 | 0.74 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL24334901 | 0.73 | PTGS2 (0.68) | PTGS2 | |
| SCHEMBL8605948 | 0.73 | POLB (0.40) | POLB | |
| SCHEMBL3110288 | 0.69 | HTR7 (0.46) | KMT2A | |
| SCHEMBL5585467 | 0.69 | HDAC1 (0.39) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4027993-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | The Broad Institute Inc. (US) | 2022-07-20 | — | — | EP | disclosed |