Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9195067 | 0.88 | GABRR1 (0.35) | GSR | |
| SCHEMBL28881933 | 0.78 | USP2 (0.39) | PTPN1 | |
| SCHEMBL850646 | 0.78 | USP2 (0.39) | PTPN1 | |
| SCHEMBL850647 | 0.78 | USP2 (0.39) | PTPN1 | |
| SCHEMBL2541174 | 0.74 | LMNA (0.39) | GSRSMPD1LMNACYP3A4NFKB1 | |
| SCHEMBL28015797 | 0.73 | GSR (0.44) | GSRCPB2RNPEPLMNACYP3A4 | |
| SCHEMBL28603061 | 0.72 | LMNA (0.38) | GSRSMPD1LMNACYP3A4NFKB1 | |
| SCHEMBL8015462 | 0.70 | GSR (0.48) | GSRCPB2RNPEPLMNABLM | |
| SCHEMBL2420751 | 0.70 | GSR (0.48) | GSRCPB2RNPEPLMNABLM | |
| Ornithine Aketoglutarate SCHEMBL21777564 | 0.70 | GSR (0.72) | GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4738554-B2 | — | — | 2011-08-03 | — | — | JP | claimed |
| EP-1021175-A4 | COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS | FOX CHASE CANCER CT (US) | 2002-08-28 | — | — | EP | claimed |
| JP-2001512424-A | — | — | 2001-08-21 | — | — | JP | claimed |
| EP-1021175-A1 | COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS | FOX CHASE CANCER CENTER (US) | 2000-07-26 | — | — | EP | claimed |
| WO-1998033492-A1 | COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS | FOX CHASE CANCER CENTER (US) | 1998-08-06 | — | — | WO | claimed |
| CN-117761174-A | Method for detecting metabolites in konjak and rhizosphere soil at different Pcc infection stages | 昆明学院 | 2024-03-26 | — | — | CN | disclosed |
| EP-1576093-A4 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS INC (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2007117394-A2 | COMPOSITIONS AND METHODS RELATED TO FRUCTOSAMINE-3-KINASE INHIBITORS | DYNAMIS THERAPEUTICS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |
| EP-1576093-A2 | 3-DEOXYGLUCOSONE AND SKIN | Dynamis Therapeutics, Inc. (US) | 2005-09-21 | — | — | EP | disclosed |
| WO-2003089601-A2 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS, INC. (US) | 2003-10-30 | — | — | WO | disclosed |