SCHEMBL2311235

SCHEMBL2311235

C=C(CN1CCOC1)C(=O)OCC

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
RECQL P46063 1/20 0.41
ALDH1A1 P00352 7/20 0.39
GAA P10253 2/20 0.39
LMNA P02545 3/20 0.39
MAPT P10636 3/20 0.39
RAB9A P51151 2/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3129789 0.90 TSHR (0.50) TSHRRECQLALDH1A1GAALMNA
SCHEMBL12764466 0.81 ALDH1A1 (0.42) TSHRALDH1A1GAAMAPTSMN1; SMN2
SCHEMBL3990594 0.81 ALDH1A1 (0.42) TSHRALDH1A1GAAMAPTSMN1; SMN2
SCHEMBL28869446 0.78 ALDH1A1 (0.40) TSHRALDH1A1GAALMNAMAPT
SCHEMBL2038297 0.77 GAA (0.41) TSHRALDH1A1GAALMNAMAPT
SCHEMBL28796394 0.76 TSHR (0.56) TSHRRECQLALDH1A1GAALMNA
SCHEMBL1198791 0.73 SMN1; SMN2 (0.49) TSHRRECQLALDH1A1GAALMNA
SCHEMBL9422139 0.72 KDM4E (0.43) TSHRALDH1A1LMNAMAPTRAB9A
SCHEMBL20567797 0.72 KDM4E (0.42) TSHRALDH1A1GAAPOLBKMT2A
SCHEMBL28123165 0.71 TSHR (0.42) TSHRRECQLALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507622-B2 Polymerizable compositions ROHM AND HAAS COMPANY (US) 2013-08-13 US disclosed
EP-2236527-B1 Improved polymerizable compostions ROHM & HAAS (US) 2011-08-17 EP disclosed
EP-2236528-B1 Improved polymerizable compositions ROHM & HAAS (US) 2011-08-03 EP disclosed
EP-2236527-A1 Improved polymerizable compostions Rohm and Haas Company (US) 2010-10-06 EP disclosed
EP-2236528-A1 Improved polymerizable compositions Rohm and Haas Company (US) 2010-10-06 EP disclosed
US-20100249365-A1 Polymerizable compositions LEMONDS ANDREW 2010-09-30 US disclosed
US-20100249348-A1 Polymerizable compositions ROHM AND HAAS COMPANY 2010-09-30 US disclosed
US-6566549-B1 Forming oligomers of vinyl acetate and oligomers of vinyl alcohol; fully saturated and terminally unsaturated oligomers ROHM AND HAAS COMPANY 2003-05-20 US disclosed
US-20020111448-A1 Continuous polymerization process and products therefrom GREENBLATT GARY DAVID (US) 2002-08-15 US disclosed
US-20020082371-A1 Continuous polymerization process and products therefrom GREENBLATT GARY DAVID (US) 2002-06-27 US disclosed
EP-1010706-A2 Continuous polymerization process and products therefrom ROHM AND HAAS COMPANY (US) 2000-06-21 EP disclosed