SCHEMBL3129789

SCHEMBL3129789

C=C(CN1CCOCC1)C(=O)OCC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
RECQL P46063 1/20 0.46
ALDH1A1 P00352 7/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 3/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.44
LMNA P02545 3/20 0.44
MAPT P10636 2/20 0.44
RAB9A P51151 2/20 0.44
POLB P06746 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2311235 0.90 TSHR (0.44) TSHRRECQLALDH1A1SMN1; SMN2KDM4E
SCHEMBL3990594 0.88 ALDH1A1 (0.42) TSHRALDH1A1SMN1; SMN2KDM4EMAPT
SCHEMBL12764466 0.88 ALDH1A1 (0.42) TSHRALDH1A1SMN1; SMN2KDM4EMAPT
SCHEMBL28869446 0.84 ALDH1A1 (0.40) TSHRALDH1A1SMN1; SMN2HSD17B10LMNA
SCHEMBL1198791 0.83 SMN1; SMN2 (0.49) TSHRRECQLALDH1A1SMN1; SMN2KDM4E
SCHEMBL2038297 0.83 GAA (0.41) TSHRALDH1A1SMN1; SMN2KDM4EHSD17B10
SCHEMBL9422139 0.81 KDM4E (0.43) TSHRALDH1A1SMN1; SMN2KDM4EHSD17B10
SCHEMBL2909869 0.79 TSHR (0.57) TSHRRECQLALDH1A1SMN1; SMN2KDM4E
SCHEMBL7058008 0.78 TSHR (0.47) TSHRRECQLALDH1A1SMN1; SMN2KDM4E
SCHEMBL7058013 0.78 TSHR (0.47) TSHRRECQLALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2906242-A1 DELIVERY OF SMALL INTERFERING RNA AND MICRO RNA THROUGH MEMBRANE-DISRUPTIVE, RESPONSIVE NANOSCALLE HYDROGELS Board Of Regents, The University Of Texas System (US) 2015-08-19 EP claimed
US-20150216814-A1 DELIVERY OF SMALL INTERFERING RNA AND MICRO RNA THROUGH MEMBRANE-DISRUPTIVE, RESPONSIVE NANOSCALLE HYDROGELS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2015-08-06 US claimed
EP-0226542-A2 Holograms ILFORD Limited (GB) 1987-06-24 EP claimed
US-11649413-B2 Lubricating oil composition for internal combustion engine ENEOS CORPORATION (JP) 2023-05-16 US disclosed
US-11274262-B2 Lubricating oil composition and use method therefor IDEMITSU KOSAN CO., LTD. (JP) 2022-03-15 US disclosed
US-20210214640-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE ENEOS CORPORATION (JP) 2021-07-15 US disclosed
US-11000602-B2 Delivery of small interfering RNA and micro RNA through nanogels containing hydrophobic pseudo-peptides BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-05-11 US disclosed
US-20210032559-A1 LUBRICATING OIL COMPOSITION AND USE METHOD THEREFOR IDEMITSU KOSAN CO.,LTD. (JP) 2021-02-04 US disclosed
CN-106471106-B Lubricating oil composition for transmission 捷客斯能源株式会社 2020-03-03 CN disclosed
CN-107075015-B Surfactant-compatibility star-like macromolecules 派诺聚合物技术公司 2019-08-23 CN disclosed
CN-109091460-A Anti-viral pharmaceutical compositions 阿尔塔纳米产品有限公司 2018-12-28 CN disclosed
US-6313191-B1 USED FOR ADHERING TO DENTAL TOOTH SURFACE DENTSPLY GMBH (DE) 2001-11-06 US disclosed
EP-1055722-A1 OIL COMPOSITION FOR NON-STAGE TRANSMISSION Japan Energy Corporation (JP) 2000-11-29 EP disclosed
US-5838863-A WATER ABSORBENT ADDITION POLYMER RESIN SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1998-11-17 US disclosed
US-5756559-A Method and composition for adhering to tooth structure DENTSPLY RESEARCH & DEVELOPMENT (US) 1998-05-26 US disclosed
EP-0790265-A1 Sealing material for cable and cable using the same SANYO CHEMICAL INDUSTRIES, Ltd. (JP) 1997-08-20 EP disclosed
EP-0765758-A2 Ink-jet recording process, and ink-jet recording apparatus CANON KABUSHIKI KAISHA (JP) 1997-04-02 EP disclosed
EP-0360617-A2 Dry toner, dry developer and process for forming images Hitachi Chemical Co., Ltd. (JP) 1990-03-28 EP disclosed
EP-0226542-A2 Holograms ILFORD Limited (GB) 1987-06-24 EP disclosed
US-4074051-A DEVELOPING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11000602-B2 Delivery of small interfering RNA and micro RNA through nanogels containing hydrophobic pseudo-peptides HNRNPH3, SNRPE, MSN TSHR 1812/4885RECQL 2635/4885ALDH1A1 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.