Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | FHIT | P49789 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23127903 | 0.85 | MAPT (0.40) | CA1CA2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23127898 | 0.80 | SLC22A12 (0.32) | CA1CA2CA12CA7TDP1 | |
| SCHEMBL23732218 | 0.71 | KMT2A (0.46) | CA1CA2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23127817 | 0.71 | KMT2A (0.43) | CA1CA2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23732255 | 0.71 | CA1 (0.40) | CA1CA2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23127813 | 0.70 | KMT2A (0.53) | KMT2AUSP2LMNAMEN1 | |
| SCHEMBL23732221 | 0.69 | ALDH1A1 (0.36) | CA1CA2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11008658 | 0.66 | ALDH1A1 (0.62) | CA1CA2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10726878 | 0.66 | ALDH1A1 (0.59) | CA1CA2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7026000 | 0.65 | TSHR (0.54) | CA1CA2ALDH1A1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112165936-B | beta-lactamase inhibitor | 国立大学法人东海国立大学机构 | 2023-11-28 | — | — | CN | disclosed |
| US-11497731-B2 | β-lactamase inhibitor | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2022-11-15 | — | — | US | disclosed |
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2021-08-05 | — | — | US | disclosed |
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2021-08-05 | — | — | US | disclosed |
| EP-3795149-A1 | INHIBITOR & X3B2;-LACTAMASE | National University Corporation Tokai National Higher Education and Research System (JP) | 2021-03-24 | — | — | EP | disclosed |
| EP-3795149-A1 | INHIBITOR & X3B2;-LACTAMASE | National University Corporation Tokai National Higher Education and Research System (JP) | 2021-03-24 | — | — | EP | disclosed |
| CN-112165936-A | Beta-lactamase inhibitors | 国立大学法人东海国立大学机构 | 2021-01-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | MGAM, CMBL, MGAM2 | CA1 1685/4885CA2 1433/4885SMN1; SMN2 3073/4885 |
| US-11497731-B2 | β-lactamase inhibitor | MGAM, CMBL, MGAM2 | CA1 2085/4885CA2 1656/4885SMN1; SMN2 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.