Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.59 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189337 | 0.89 | CYP2A6 (0.73) | HSD17B10CYP2A6CYP2A13ALDH1A1ALDH3A1 | |
| SCHEMBL29429137 | 0.83 | HSD17B10 (0.73) | HSD17B10CYP2A6CYP2A13ALDH1A1ALDH3A1 | |
| Ethane SCHEMBL2154693 | 0.82 | HSD17B10 (0.89) | HSD17B10CYP2A6CYP2A13ALDH1A1ALDH3A1 | |
| SCHEMBL5213200 | 0.82 | CHKA (0.55) | HSD17B10CYP2A6ALDH1A1CHKAKDM4E | |
| SCHEMBL1919 | 0.82 | — | — | |
| SCHEMBL95663 | 0.81 | CYP2A6 (0.61) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL11843859 | 0.81 | CYP2A6 (0.70) | HSD17B10CYP2A6CYP2A13ALDH1A1ALDH3A1 | |
| SCHEMBL11850274 | 0.80 | HSD17B10 (0.61) | HSD17B10CYP2A6CYP2A13ALDH1A1ALDH3A1 | |
| Methyl Alcohol SCHEMBL28044962 | 0.80 | HSD17B10 (0.84) | HSD17B10CYP2A6CYP2A13ALDH1A1ALDH3A1 | |
| Hydrochloric Acid SCHEMBL6414496 | 0.79 | CHKA (0.53) | HSD17B10CYP2A6ALDH1A1CHKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341371-A | As LTC4Bis-aromatic compounds as synthase inhibitors | BIOLIPOX AB (SE) | 2012-02-01 | — | — | CN | disclosed |
| EP-2406220-A1 | BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS | Biolipox AB (SE) | 2012-01-18 | — | — | EP | disclosed |
| EP-2406223-A2 | BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS | Biolipox AB (SE) | 2012-01-18 | — | — | EP | disclosed |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| US-20110319431-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2011-12-29 | — | — | US | disclosed |
| WO-2010103279-A1 | BIS AROMATIC COMPOUNDS FOR USE AS LCT4 SYNTHASE INHIBITORS | BIOLIPOX AB (SE) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010103297-A2 | BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS | BIOLIPOX AB (SE) | 2010-09-16 | — | — | WO | disclosed |
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319431-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | HSD17B10 655/4885CYP2A6 136/4885CYP2A13 75/4885 |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | HSD17B10 438/4885CYP2A6 215/4885CYP2A13 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.