SCHEMBL23113326

SCHEMBL23113326

NC(=O)c1cnc(N2CCC[C@H](N)C2)nc1Nc1cc(C(=O)N2CCOCC2)cc(-c2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CAMK1D Q8IU85 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28496606 1.00 CAMK1D (1.00) CAMK1D
SCHEMBL23113403 0.91 CAMK1D (1.00) CAMK1D
SCHEMBL23113549 0.91 CAMK1D (0.87) CAMK1D
SCHEMBL24736224 0.91 CAMK1D (1.00) CAMK1D
SCHEMBL23113334 0.91 CAMK1D (0.83) CAMK1D
SCHEMBL23113461 0.88 CAMK1D (1.00) CAMK1D
SCHEMBL23113463 0.88 CAMK1D (1.00) CAMK1D
SCHEMBL23113697 0.88 CAMK1D (1.00) CAMK1D
SCHEMBL23113242 0.88 CAMK1D (1.00) CAMK1D
SCHEMBL23113230 0.88 CAMK1D (1.00) CAMK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11530193-B2 Kinase inhibitors THE UNIVERSITY OF MANCHESTER (GB) 2022-12-20 — — US disclosed
EP-3793996-A1 KINASE INHIBITORS The University of Manchester (GB) 2021-03-24 — — EP disclosed
CN-112119077-A Kinase inhibitors 曼彻斯特大学 2020-12-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530193-B2 Kinase inhibitors CAMKK2, CAMK1, CAMKK1 CAMK1D 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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