Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566131 | 0.81 | HSD11B1 (0.39) | HSD11B1DHFRMEN1KMT2APTPN1 | |
| SCHEMBL1755976 | 0.78 | HSD11B1 (0.41) | HSD11B1DHFRMEN1KMT2APTPN1 | |
| SCHEMBL15102152 | 0.77 | HSD11B1 (0.43) | HSD11B1DHFRMEN1KMT2APTPN1 | |
| SCHEMBL2017636 | 0.77 | HSD11B1 (0.40) | HSD11B1DHFRMEN1KMT2ATNK2 | |
| SCHEMBL5535487 | 0.77 | HSD11B1 (0.40) | HSD11B1DHFRMEN1KMT2ATNK2 | |
| SCHEMBL3451372 | 0.77 | HSD11B1 (0.43) | HSD11B1DHFRMEN1KMT2ATNK2 | |
| SCHEMBL7159270 | 0.77 | HSD11B1 (0.43) | HSD11B1DHFRMEN1KMT2APTPN1 | |
| SCHEMBL24177158 | 0.75 | AR (0.41) | HSD11B1DHFRMEN1KMT2ATNK2 | |
| SCHEMBL20004827 | 0.75 | HSD11B1 (0.41) | HSD11B1DHFRMEN1KMT2APTPN1 | |
| SCHEMBL16318984 | 0.74 | HSD11B1 (0.40) | HSD11B1DHFRMEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094450-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC (US) | 2011-08-04 | — | — | WO | disclosed |