Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755976 | 0.90 | HSD11B1 (0.41) | HSD11B1NPC1RAB9APTPN1PDE4B | |
| SCHEMBL10923350 | 0.87 | CA12 (0.46) | HSD11B1NPC1RAB9APTPN1PDE4B | |
| SCHEMBL15100429 | 0.83 | PTPN1 (0.43) | HSD11B1NPC1RAB9APTPN1PDE4B | |
| SCHEMBL15100385 | 0.83 | PTPN1 (0.43) | HSD11B1NPC1RAB9APTPN1PDE4B | |
| SCHEMBL2893577 | 0.83 | NPC1 (0.40) | HSD11B1NPC1RAB9APTPN1PDE4B | |
| SCHEMBL15100426 | 0.83 | PTPN1 (0.43) | HSD11B1NPC1RAB9APTPN1PDE4B | |
| SCHEMBL3451372 | 0.83 | HSD11B1 (0.43) | HSD11B1NPC1RAB9APDE4BDHFR | |
| SCHEMBL7242085 | 0.82 | NPC1 (0.46) | HSD11B1NPC1RAB9APTPN1PDE4B | |
| SCHEMBL7157436 | 0.81 | LMNA (0.41) | HSD11B1NPC1RAB9APTPN1PDE4B | |
| SCHEMBL29394265 | 0.80 | ALDH1A1 (0.54) | NPC1RAB9APTPN1PDE4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |